CINNAMON BOOSTS COLLAGEN PRODUCTION THROUGH IGF-1
Acinnamon supplement can help against skin aging, concluded biochemists at Osaka Prefecture University in Japan from a study in which they exposed skin cells to extracts of ten edible herbs in test tubes. If you’re a supplements or cosmetics manufacturerer looking for products to reduce skin aging, there are two factors ors you need to take into account: collagen and IGF-1. Skin owes its suppleness and youthfulness to a high level of collagen synthesis by the skin cells, and the hormone that stimulates the skin cells to produce collagen is IGF-1. There are indications that molecules in our food can enhance the effect of insulin – which in many respects resembles the effect of IGF-1. That’s why these researchers wondered whether they could find these molecules in edible herbs. When the Japanese exposed skin cells to ten different herb extracts in test tubes, they noticed that fenugreek, cinnamon and Iranian cumin in particular boosted collagen production. Cinnamaldehyde in particular enhanced collagen synthesis, the researchers discovered. Cinnamaldehyde improves the performance of IGF-1, the researchers discovered. They discovered more phosphorylated IGF-1 receptors in skin cells that had been exposed to IGF-1 rather than to cinnamaldehyde. So cinnamaldehyde doesn’t lead to the creation of more IGF-1 receptors, but does ensure that, once e IGF-1 has attached itself to its receptor, that the signal is transmitted better to the cell. The same actually also happened in experiments without IGF-1, so it would seem that cinnamaldehyde can replace IGF-1 in skin cells. [Hmm... we wonder if cinnamaldehyde does the same in muscle cells...] Reference: J Agric Food Chem. 2012 Feb.