Amazing Spider-Man #361
If you thought Venom was bad, wait until you meet his son. Well, not really. Carnage was another symbiote, created when Venom briefly bonded to Eddie Brock’s former cellmate, psychopathic Cletus Kasady. With added psycho-ness from Cletus in the mix, Spidey was forced to go to none other than Venom to help bring the newcomer to book. Venom agreed but SpiderMan, in a rare display of churlishness, roped in Mr Fantastic to get Venom banged up as well. Which ultimately did nothing for their relationship.