Get the tone
The Maiden sound is Strat and Marshall. Dave and Janick use a variety of Fenders, while Adrian favours his Jackson. All three have humbuckers at the bridge for a fat, riffing tone. You'll get close to the sound with any humbucking guitar, but if you have single-coils you can fatten it with more gain, bass and mid. Amp-wise it's either Marshall 100w JCM2000 heads or JMP1 preamps. Don’t use too much gain as this can sap the tone and you’ll lose the natural body of the guitar sound.