Get the tone
On the GT tracks the overdrive settings are mostly quite light, allowing picking to be clearly heard. So bear in mind that if you use too much distortion clarity will diminish and it becomes harder to identify issues that need resolving. Try a clean tone and a dash of reverb; this is pretty unforgiving and will reveal any problems; a clean tone also forces you to use touch and technique to achieve nicely rounded notes. If this a little too hardcore then start by halving your distortion levels; remember, if it sounds great clean, it will sound even better with some crunch!