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ELLEN Pom­peo (above), who plays Meredith Grey in Grey’s Anatomy, is cer­tain she has worked out the se­cret to the show’s huge in­ter­na­tional suc­cess.

‘‘Clearly, the show is a com­bi­na­tion of edit­ing and writ­ing, but I think the one thing that is very hard to deny is, de­spite how crazy the sto­ry­lines get, the fans are still there,’’ Pom­peo says.

‘‘And I think that’s be­cause of the in­her­ent chem­istry of the cast. For some rea­son that I don’t know you can quan­tify, we have some sort of chem­istry, all of us.

‘‘No mat­ter how ridicu­lous the sto­ry­lines seem, the ac­tors are able to pull it off be­cause we have this en­ergy that runs be­tween us. That’s why the fans are kind enough to stick with us through sto­ry­lines that don’t fol­low through or don’t make sense.

‘‘There’s a chem­istry be­tween us that keeps the dy­namic in­ter­est­ing to watch. I think the ac­tors are just tremen­dous.’’

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