I often draw and paint in a sculptural way, and the best tool for this approach is the Pencil tool as opposed to the softer Brush tool. I’m not eschewing the Brush tool entirely, but my heavy lifting is done with the Pencil. Its anti-aliased edge provides some distinct advantages. Images remain sharp even after a lot of blending, and that clarity reflects in print. Furthermore, the Pencil tool is less taxing on the system resources.