New cancer drug will ‘starve’ cells
Scientists have found a way to kill cancer cells by starving them of the fuel they need.
A world-first breakthrough by a Sydney team has identified what drives difficult-to-quash cancer cells that cause the most deadly breast, prostate and skin cancers.
Centenary Institute Associate Professor Jeff Holst led the study that found these notorious cancer cells thrive on an amino acid called glutamine but normal cells do not.
“Cancer cells have found ways to use glutamine to fuel their growth and they become addicted,” Professor Holst said.
“They are so dependent on it that if you take it away the cells die.”
Professor Holst is developing a drug which stops the cells taking in glutamine.
The drug is expected to enter clinical trials in as little as three years.