SEASON 1: Meet Nina and her bundle of neuroses, Billie and her desperate wish for children, and a hottie named Dr Chris Havel (Don Hany) who Nina hooks up with, only to find he’s married. Then Nina sleeps with Billie’s bloke Mick (Eddie Perfect) – and bolts out of Melbourne for a job in Baltimore.
SEASON 2: The sisters reconcile, Nina returns to Melbourne. Dr Chris has moved to Brisbane. Enter Dr Patrick Reid (Matt Le Nevez) – Nina’s new love – until Dr Chris returns, and she has to choose.
SEASON 3: Nina chooses Patrick. They move in. They break up. She’s pregnant, then she’s not, then she is. Meanwhile, Billie struggles to fall pregnant.
SEASON 4: Nina and Patrick are back together. Things blow apart with Patrick’s death, and the birth of their baby Zoe.
SEASON 5: Six months after Patrick’s death, Billie blossoms as she helps Nina with Zoe, but is devastated by her break-up with Mick. Nina struggles with grief, motherhood and new relationships. Toddler Alfie falls terribly ill. A mother dies in childbirth. Nina’s new bloke, Thomas, is exposed as a married, two-timing liar. Fans say “enough sadness already”.