Why Cannabis Works for Pain

ZOOMER Magazine - - VITALITY -

The En­do­cannabi­noid Sys­tem

Each of us has an en­do­cannabi­noid sys­tem (ECS), just like a ner­vous sys­tem and a di­ges­tive sys­tem. It’s in­volved in many bod­ily pro­cesses, in­clud­ing pain-sen­sa­tion. Some med­i­cal con­di­tions af­fect the proper func­tion­ing of the ECS, lead­ing to pain. The ECS nat­u­rally pro­duces chem­i­cals sim­i­lar to those in cannabis. These chem­i­cals pass mes­sages be­tween the brain and body parts through neu­rons and re­cep­tors.

The Cannabi­noids in Cannabis

The cannabi­noids in cannabis sup­ple­ment the cannabi­noids nor­mally pro­duced by the ECS. They bind to pain re­cep­tors and al­le­vi­ate the pain sig­nals sent to the brain. THC (delta-9tetrahy­dro­cannabi­nol) causes the psy­choac­tive ef­fects or “high” felt from cannabis. It helps with symp­toms such as in­flam­ma­tion and pain, in­som­nia, and nau­sea and vom­it­ing. CBD (cannabid­iol) has al­most no psy­choac­tive ef­fect. It helps with in­flam­ma­tion and seizures and acts as an an­tide­pres­sant, work­ing on sim­i­lar re­cep­tors to med­i­ca­tions that act on sero­tonin re­cep­tors.

Neu­ron Re­cep­tors Cannabi­noids The dots are the lo­ca­tions in the body where cannabi­noids act on the ECS.

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