Scientists create mice without sperm
In a major reproductive breakthrough, scientists in Shanghai have created mice by using two eggs and no sperm.
The team achieved the pioneering feat by modifying an egg and making it work as a sperm replacement that is injected in another egg to activate fertilization. A paper on their discovery was published in the Chinabased international scientific journal Cell Research on Nov 17.
They promoted cell division of a mature egg through chemical means and created a line of cells. After modifying one cell by removing two genes, they injected the cell into another egg as part of artificial fertilization process.
“In our experiments, more than 15 out of 100 embryos finally developed into mice. They are healthy and show no difference in development and fertility from the ones that are naturally conceived,” said Zhong Cuiqing, one of the researchers in the team at Shanghai Institutes for Biological Sciences under the Chinese Academy of Sciences.