Scientists conduct genetic analysis of Chinese
Chinese and American scientists have sequenced and analyzed a portion of genomes of more than 140,000 pregnant women in China, the largestscale genetic analysis of Chinese people to date.
It reveals associations between genes and birth outcomes, including the birth of twins and a woman’s age at first pregnancy.
The study published in the journal Cell also allowed researchers to reconstruct the intermarriage of different ethnic groups in China and promised to help identify genes that make people susceptible infectious diseases.
Researchers from BGI-Shenzhen used data from non-invasive prenatal testing (NIPT) to sequence randomly 6 to 10 percent of each mother’s genome.
They found that the variation in a gene called NRG1 was linked to a greater or lesser incidence of twins. One variant of the gene is more common in mothers with twins and is associated with hyperthyroidism. A variant of another gene, EMB, was associated with older first-time mothers, according to the study. to