Sci­en­tists con­duct ge­netic anal­y­sis of Chi­nese

China Daily (Canada) - - NEWS CAPSULE -

Chi­nese and Amer­i­can sci­en­tists have se­quenced and an­a­lyzed a por­tion of genomes of more than 140,000 preg­nant women in China, the largestscale ge­netic anal­y­sis of Chi­nese peo­ple to date.

It re­veals as­so­ci­a­tions be­tween genes and birth out­comes, in­clud­ing the birth of twins and a woman’s age at first preg­nancy.

The study pub­lished in the jour­nal Cell also al­lowed re­searchers to re­con­struct the in­ter­mar­riage of dif­fer­ent eth­nic groups in China and promised to help iden­tify genes that make peo­ple sus­cep­ti­ble in­fec­tious dis­eases.

Re­searchers from BGI-Shen­zhen used data from non-in­va­sive pre­na­tal test­ing (NIPT) to se­quence ran­domly 6 to 10 per­cent of each mother’s genome.

They found that the vari­a­tion in a gene called NRG1 was linked to a greater or lesser in­ci­dence of twins. One vari­ant of the gene is more com­mon in moth­ers with twins and is as­so­ci­ated with hy­per­thy­roidism. A vari­ant of an­other gene, EMB, was as­so­ci­ated with older first-time moth­ers, ac­cord­ing to the study. to

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