World is run­ning out of an­tibi­otics: WHO

BioSpectrum (Asia) - - Who News -

An­tibi­otics that are cur­rently in clin­i­cal devel­op­ment are in­suf­fi­cient to com­bat the grow­ing threat of antimicrobial re­sis­tance, as stated by World Health Or­gan­i­sa­tion (WHO) re­port.

Most of the drugs cur­rently in the clin­i­cal phase are mod­i­fi­ca­tions of ex­ist­ing classes of an­tibi­otics and are only short-term so­lu­tions.

There are, how­ever, very few po­ten­tial treat­ment op­tions. The grow­ing re­sis­tant in­fec­tions pose the great­est threat to health, in­clud­ing drug-re­sis­tant tu­ber­cu­lo­sis (TB) which kills around 250,000 peo­ple each year. There are also very few oral an­tibi­otics in the pipe­line, yet these are essen­tial for­mu­la­tions for treat­ing in­fec­tions out­side hos­pi­tals or in re­source-limited set­tings.

Be­sides TB, the WHO has also iden­ti­fied 12 classes of pri­or­ity pathogens, in­clud­ing com­mon in­fec­tions like pneu­mo­nia or uri­nary tract in­fec­tions that are in­creas­ingly re­sis­tant to ex­ist­ing an­tibi­otics and ur­gently in need of new treat­ments.

Among the newly iden­ti­fied 51 new an­tibi­otics and bi­o­log­i­cals in clin­i­cal devel­op­ment, only eight are classed by WHO as in­no­va­tive treat­ments that will add value to the cur­rent an­tibi­otic treat­ment ar­se­nal.

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