Bill Gates in­tro­duces de­men­tia Di­ag­nos­tics Ac­cel­er­a­tor

BioSpectrum (India) - - WORLD NEWS -

Bill Gates has an­nounced the introduction of the Di­ag­nos­tics Ac­cel­er­a­tor, a project of the Alzheimer’s Drug Dis­cov­ery Foun­da­tion (ADDF), to fur­ther ideas for ear­lier and bet­ter di­ag­no­sis of Alzheimer’s disease. Gates is lead­ing the fund­ing with a $30 mil­lion in­vest­ment.

The project is set up as a ven­ture cap­i­tal fund, bring­ing to­gether biotech com­pa­nies, aca­demics, char­i­ties and other part­ners. One of the main bot­tle­necks in Alzheimer’s drug de­vel­op­ment has been a lack of val­i­dated biomark­ers to di­ag­nose pa­tients non­in­va­sively, mon­i­tor pro­gres­sion or re­veal sub­groups that may ben­e­fit from spe­cific ther­a­pies in clin­i­cal tri­als. Cur­rently, the only way to defini­tively di­ag­nose the disease is through an au­topsy; tests of cog­ni­tive de­cline need to rule out other pos­si­ble causes. Positron emis­sion to­mog­ra­phy scans can be used to de­tect amy­loid plaque de­posits in the brain, but the tech­nol­ogy is not widely avail­able and car­ries high ra­di­a­tion ex­po­sure.

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