Rice starch may pro­vide a drug delivery method

Chemical Industry Digest - - News & Views -

Ateam of re­searchers from Uni­ver­sity of Kash­mir found that rice starch may pro­vide a drug delivery method sys­tem for trans­port­ing pro­bi­otics through acidic up­per gas­troin­testi­nal tract.

The re­search led by Adil Gani, an As­sis­tant Pro­fes­sor at the Depart­ment of Food Sci­ence and Tech­nol­ogy, has shown that chem­i­cally tweak­ing starch present in rice can de­velop a sub­stance called RS-4, that can pro­tect ben­e­fi­cial gut bac­te­ria from get­ting in­gested in stom­ach when con­sumed orally.

The find­ings are pub­lished in the jour­nal, Food Chem­istry, re­ported that this drug delivery sys­tem could be ex­ploited to de­liver orally ad­min­is­tered pro­bi­otic bac­te­ria into the colon.

“As we age, there is a de­ple­tion in the gut mi­croflora and the ef­forts to de­liver these ben­e­fi­cial bac­te­ria to gut- so as to keep the right mi­cro­bial balance- suf­fers se­ri­ously as to keep right mi­cro­bial balance- suf­fers se­ri­ously as the up­per gas­troin­testi­nal tract in­gests most of it,” said Gani. This delivery sys­tem is not just cheap and can be used for other drugs too, as it is ca­pa­ble of de­liv­er­ing them where the ac­tion should be”, he added.

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