Arthri­tis cure on the cards ?

Down to Earth - - SCIENCE -

SCI­EN­TISTS HAVE suc­ceeded in cur­ing rheuma­toid arthri­tis in mice. Arthri­tis causes swelling and in­flam­ma­tion in joints and can de­stroy the car­ti­lage and bone. The new ther­apy uses a com­bi­na­tion of two com­po­nents: body's own im­mune mes­sen­ger in­ter­leukin 4 (IL-4) and an an­ti­body to IL-4 that binds to a pro­tein found only in in­flamed tis­sues. This fused mol­e­cule en­sures that the drug tar­gets only in­flamed ar­eas. This mol­e­cule, in com­bi­na­tion with a common arthri­tis drug dex­am­etha­sone, was found to have com­pletely cured mice of arthri­tis. PNAS, Au­gust 4

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