New weapon against can­cer

Down to Earth - - SCIENCE - mBio, April 14

GE­NET­I­CALLY MOD­I­FIED Sal­monella en­ter­ica can be used to kill can­cer cells, shows a re­cent study. Re­searchers fo­cused on mod­i­fy­ing the lipopolysac­cha­ride struc­ture in the walls of the Sal­monella strain to make the bac­te­ria less toxic so that they would not harm healthy cells, but can ef­fec­tively colonise tu­mours and would turn toxic af­ter en­ter­ing can­cer cells. The ther­apy would be used in con­junc­tion with chemo­ther­apy and ra­di­a­tion once it gets to hu­man tri­als.

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