A filler is a safe and natural substance used to fill the dermis (deeper skin). More often used on the lower portion of the face, fillers target nose-to-mouth lines, ‘marionette’ lines around the mouth and smokers’ lines on the upper lip. These are also used for lip plumping and cheek sculpting. Fillers usually produce an immediate result, the effects of which last for 6-9 months. There may be redness, swelling, tenderness, itching or discolouration of skin around the injection site, typically lasting for a few hours to 1-2 days.