The latest technologies are now available at PFRC
INTRACYTOPLASMIC MORPHOLOGICALLY SELECTED SPERM INJECTION (IMSI )
A new computer Assisted technique to identify morphologically normal structure for patients with abnormal sperms. IMSI is based on selecting the best sperm under a magnification of more than 6000x. Using this magnification morphological defects, even small vacuoles become apparent.
The technique is harmless and safe and leads to better embryo development, higher pregnancy rates and lower miscarriage rates. This is a real boon for patients with repeated IVF failures and those with recurrent miscarriages. Intracytoplasmic Morphologically selected Sperm Injection (IMSI ) is considered by some experts an effective treatment for male factor Infertility. The technique involves selecting the best quality sperm cells from the prepared semen sample by examining under a high magnification microscope which is about 7000 times more powerful than the standard microscope. Exploring at this magnification shows defects in sperm heads, shapes and size and any abnormalities associated with high DNAfragmentation, which cannot be seen with the conventional microscope used for ICSI. The digital image processing provides additional image enhancement (over 6000 time) for detail recognition by the operator. The IMSI will be useful for patients who have had repeated ICSI failers, very low sperm count and large numbers of abnormals.
The technique of IMSI was developed by Prof. BARTOOV – of ISRAEL in 2002. He and his team conducted a research to see which morphological character of sperm affected the outcome of ICSI pregnancy and showed that there was a significant improvement in implantation, pregnancy and birth rates using IMSI in patents with 2 or more unsuccessful ICSI cycles.