All 4 dengue strains can cir­cu­late to­gether, turn deadly: study

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The re­search was also pub­lished in the

As many as 1,536 (28%) of the 5,536 pa­tients tested dur­ing the study in the NIMR clinic had con­firmed dengue. The peak dengue pos­i­tiv­ity was seen dur­ing Septem­ber and Oc­to­ber, said the study.

“Of the 60 sam­ples an­a­lysed, 10 (16.7%) had con­cur­rent in­fec­tion with mul­ti­ple dengue serotypes; one of them had all the four serotypes. Co-in­fec­tion of dengue with malaria and chikun­gunya was also ob­served. In­fec­tion with more than one serotype was also ob­served. Dengue and malaria co-in­fec­tion was also found though malaria trans­mis­sion is very low in Delhi,” said Deepali Savar­gaonkar, a sci­en­tist with NIMR and the au­thor of the study.

“Delhi be­ing hyper-en-

Dis­ease bur­den demic to dengue and other vec­tor-borne dis­eases, the oc­cur­rence of con­cur­rent in­fec­tions with mul­ti­ple DENV serotypes has be­come a fre­quent find­ing. There is a need for strong sur­veil­lance to mon­i­tor trends in dengue dis­tri­bu­tion, sea­sonal pat­terns and cir­cu­lat­ing serotypes to guide dengue con­trol ac­tiv­i­ties,” she said.

There is a sig­nif­i­cant as­soc­i­to­gether. ation of peak in dengue pos­i­tiv­ity and high lar­val indices with the post-mon­soon pe­riod, the sci­en­tists have pointed out. Dengue is seen to be com­mon in the age groups of 11-20 and 21-30 as they are more prone to mos­quito bites be­cause of the na­ture of their daily rou­tine, they said.

“Dengue is preva­lent in at least 128 coun­tries. With in­creased glob­al­iza­tion and ma­jor trav­el­ling, the pos­si­bil­ity of co-in­fec­tion of virus’s strains has largely in­creased. As peo­ple travel, they can bring dif­fer­ent strains from other places,” said Him­mat Singh, a sci­en­tist with NIMR.

“If a mos­quito car­ry­ing one strain bites a per­son car­ry­ing a dif­fer­ent strain, the mos­quito gets the new strain as well and fur­ther spreads it. Dengue co-in­fec­tion with its own strains and malaria and chikun­gunya can be much more se­vere than thought,” Singh said.

“In ar­eas en­demic for dengue, chikun­gunya and malaria, there is a need to have a higher de­gree of sus­pi­cion of co-in­fec­tion to en­sure prompt treat­ment, es­pe­cially for malaria. With fre­quent out­breaks in Delhi, there is a need to con­duct epi­demi­o­log­i­cal and en­to­mo­log­i­cal sur­veil­lance, which will help in early warn­ing of out­break and con­trol of dengue,” said Savar­gaonkar.

At least 40,868 cases of dengue have been re­ported with 83 deaths till 30 Septem­ber 2018, ac­cord­ing to the Na­tional Vec­tor Borne Dis­ease Con­trol Pro­gramme un­der the min­istry of health and fam­ily wel­fare. The high­est bur­den of the dis­ease is in Ma­ha­rash­tra (4.667 cases), Odisha (3,883) and Ker­ala (3,660). Ker­ala has recorded the high­est num­ber of deaths, 35, fol­lowed by Ma­ha­rash­tra (18) and Ch­hat­tis­garh (10).

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