Vitamin D in adults

The Hindu Business Line - - PULSE -

Vitamin D sup­ple­men­ta­tion does not pre­vent frac­tures or falls, or im­prove bone min­eral den­sity in adults, ac­cord­ing to a new meta-anal­y­sis of 81 ran­domised tri­als pub­lished in The Lancet Di­a­betes & En­docrinol­ogy jour­nal. Fur­ther­more, the study found no dif­fer­ences in the ef­fects of higher ver­sus lower doses of vitamin D. The au­thors con­clude that there is there­fore lit­tle jus­ti­fi­ca­tion to use vitamin D sup­ple­ments to main­tain or im­prove mus­cu­loskele­tal health, ex­cept for the pre­ven­tion of rare con­di­tions such as rick­ets and os­teo­ma­la­cia in high risk groups, which can oc­cur due to vitamin D de­fi­ciency af­ter a pro­longed lack of ex­po­sure to sunshine. Vitamin D sup­ple­ments have long been rec­om­mended for older peo­ple to treat or pre­vent os­teo­poro­sis, with some early ev­i­dence sug­gest­ing ben­e­fits for bone health. How­ever, re­cent large-scale re­views have re­ported no ef­fect of vitamin D sup­ple­men­ta­tion on bone min­eral den­sity, falls or frac­tures. “On the strength of ex­ist­ing ev­i­dence, we be­lieve there is lit­tle jus­ti­fi­ca­tion for more tri­als of vitamin D sup­ple­ments look­ing at mus­cu­loskele­tal out­comes,” says a note from the jour­nal.

Newspapers in English

Newspapers from India

© PressReader. All rights reserved.