Ira­nian sci­en­tist, col­leagues de­velop ban­dage that de­liv­ers meds au­tonomously

Tehran Times - - SCIENCE - (Source: mehrnews.com)

A team of re­searchers from the Univer­sity of Ne­braska, Har­vard med­i­cal school and MIT have de­vel­oped a ban­dage that re­leases med­i­ca­tion over time.

The med­i­cal ban­dage is made of elec­tri­cally con­duc­tive fibers coated with hy­dro­gel. The gel con­tains med­i­ca­tion such as an­tibi­otics, growth fac­tor and painkillers mean­ing that one ban­dage could con­tain sev­eral med­i­ca­tions.

An in­te­grated mi­cro­con­troller sends volt­age through dif­fer­ent fibers at dif­fer­ent times after which those fibers heat up, also heat­ing the gel that cov­ers them. This causes the gel to re­lease med­i­ca­tion into the wound.

The mi­cro­con­troller could be trig­gered wire­lessly, by a smart­phone or a tablet. It’s also pos­si­ble to in­cor­po­rate thread-based sen­sors into the ban­dage. These sen­sors would mea­sure glu­cose, pH and other in­di­ca­tors of skin health. Ac­cord­ingly, the ban­dage could au­tonomously trig­ger it­self to de­liver med­i­ca­tion.

The tech­nol­ogy could be used on di­a­betic or other chronic wounds, or for sol­diers on the bat­tle­field where many pathogens exit.

“This is the first ban­dage that is ca­pa­ble of dose-de­pen­dent drug re­lease,” says Ali Ta­mayol, Univer­sity of Ne­braska’s Ira­nian as­sis­tant pro­fes­sor and direc­tor of the re­search team. “You can re­lease mul­ti­ple drugs with dif­fer­ent re­lease pro­files. That’s a big ad­van­tage in com­par­i­son with other sys­tems. What we did here was come up with a strat­egy for build­ing a ban­dage from the bot­tom up.”

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