Wine, choco­late good for cells

The Sun (Malaysia) - - LIFESTYLE -

A COM­POUND in dark choco­late and red wine could help re­ju­ve­nate cells, ac­cord­ing to a sci­en­tific break­through.

Re­searchers from the Uni­ver­si­ties of Ex­eter and Brighton made a size­able break­through on age­ing, and dis­cov­ered a way to re­ju­ve­nate in­ac­tive senes­cent cells.

The re­searchers ap­plied com­pounds called re­ver­satrol ana­logues, which are chem­i­cals based on a sub­stance nat­u­rally found in red wine, dark choco­late, red grapes and blue­ber­ries, to cells in cul­ture.

Pre­vi­ous re­search by the Univer­sity of Ex­eter had found that a class of genes called ‘splic­ing fac­tors’ are pro­gres­sively switched off as we age.

But the new study found that ap­ply­ing the re­ver­satrol ana­logues to the cells caused splic­ing fac­tors to be switched back on.

Within hours of treat­ment, older cells had started to di­vide and had longer telom­eres, which are the ‘caps’ on the chro­mo­somes which shorten as we age.

The re­searchers hope that the break­through could lead to ther­a­pies that help peo­ple age bet­ter, and with­out many of the de­gen­er­a­tive prob­lems peo­ple en­counter as we get older.

Prof Lorna Har­ries, a pro­fes­sor of Molec­u­lar Ge­net­ics at the Univer­sity of Ex­eter, said: “This is a first step in try­ing to make peo­ple live nor­mal life­spans, but with health for their en­tire life.

“Our data sug­gests that us­ing chem­i­cals to switch back on the ma­jor class of genes that are switched off as we age might pro­vide a means to re­store func­tion to old cells.”

Har­ries went on to ex­plain that the re­search proves that the cells can be treated to re­gain some features of youth.

Dr Eva Latorre, a re­search as­so­ciate at the Univer­sity of Ex­eter, who car­ried out the ex­per­i­ments, was sur­prised by the ex­tent and ra­pid­ity of the changes in the cells.

“When I saw some of the cells in the cul­ture dish re­ju­ve­nat­ing I couldn’t be­lieve it,” she said.

“I re­peated the ex­per­i­ments sev­eral times and, in each case, the cells re­ju­ve­nated. I am very ex­cited by the im­pli­ca­tions and po­ten­tial for this re­search.” – The In­de­pen­dent

Newspapers in English

Newspapers from Malaysia

© PressReader. All rights reserved.