Study says Tdap vac­cine safe dur­ing preg­nancy

Daily Trust - - HEALTH -

Even if a woman gets a tetanus-con­tain­ing shot be­fore she con­ceives, it is still safe to give her the tetanus­con­tain­ing Tdap vac­cine while she is preg­nant, new re­search in­di­cates.

As it stands, fed­eral guide­lines state that the Tdap vac­cine, which also guards against diph­the­ria and per­tus­sis (whoop­ing cough), is rec­om­mended for ev­ery woman dur­ing ev­ery preg­nancy.

How­ever, there has been a lack of re­search on the safety of giv­ing the vac­cine dur­ing preg­nancy, the re­searchers noted. And some women have of­ten balked at the rec­om­men­da­tion.

“Preg­nant pa­tients are of­ten re­luc­tant to take med­i­ca­tions, es­pe­cially vac­ci­na­tions,” ex­plained Dr. Jen­nifer Wu, an ob­ste­tri­cian/gy­ne­col­o­gist at Lenox Hill Hospi­tal in New York City, who was not in­volved with the study. “Re­cent rec­om­men­da­tions for Tdap vac­cines are of­ten met with re­sis­tance from pa­tients. Some of the fore­most con­cerns are safety to the fe­tus, and also safety to the mother, if she has had this vac­ci­na­tion in the past.”

But the new study should help put those fears to rest, the re­searchers said.

“Our find­ings should re­as­sure pa­tients and clin­i­cians who might be hes­i­tant to give Tdap vac­cine to preg­nant women who re­cently re­ceived a Tdap or other tetanus­con­tain­ing vac­ci­na­tion,” wrote study author Dr. Lak­shmi Suku­maran, from the U.S. Cen­ters for Dis­ease Con­trol and Preven­tion, and col­leagues. An­other ex­pert con­curred. “The vac­ci­na­tion can be given at any time dur­ing preg­nancy as it is not a live vac­cine,” said Dr. Tracy Adams, a ma­ter­nal-fe­tal medicine spe­cial­ist at Winthrop-Univer­sity Hospi­tal in Mi­ne­ola, N.Y. “This study adds to the grow­ing body of ev­i­dence that sug­gests the safe use of in­ac­ti­vated virus or bac­te­rial vac­cines or tox­oids in preg­nancy in or­der to pre­vent dis­ease in both mother and child.”

Mean­while, the Tdap vac­cine pro­tects against whoop­ing cough, which has in­creased in preva­lence over the past decade in the United States, the re­searchers pointed out. And new­borns and in­fants are more likely to be hos­pi­tal­ized or die from whoop­ing cough than older chil­dren and adults.

In the study, the re­searchers an­a­lyzed data from more than 29,000 women who re­ceived Tdap in preg­nancy in Cal­i­for­nia, Colorado, Min­nesota, Ore­gon, Wash­ing­ton and Wis­con­sin. They com­pared out­comes among those women who had re­ceived a tetanus-con­tain­ing vac­cine less than two years be­fore preg­nancy, two to five years be­fore preg­nancy and more than five years be­fore preg­nancy.

Re­gard­less of how long it had been since the women last re­ceived a tetanus-con­tain­ing vac­cine, there were no sig­nif­i­cant dif­fer­ences in rates of fever, al­lergy or lo­cal re­ac­tions among moth­ers or in rates of small for ges­ta­tional age, pre­ma­ture birth and low birth weight among in­fants.

The study au­thors added that fur­ther re­search is needed to de­ter­mine if giv­ing Tdap vac­cine to preg­nant women who re­cently re­ceived a tetanus-con­tain­ing vac­cine in­creases the risk of still­birth or mis­car­riage.

The study was pub­lished Oct. 20 in the Jour­nal of the Amer­i­can Med­i­cal As­so­ci­a­tion.

Newspapers in English

Newspapers from Nigeria

© PressReader. All rights reserved.