h4ufme (Singapore) - - Clips -

A study pub­lished online in PLOS ONE re­vealed that hu­man stem cells are used in a study to gen­er­ate new hair, a first step that rep­re­sents in de­vel­op­ing a cell-based treat­ment for peo­ple ex­pe­ri­enc­ing hair loss.

Med­i­cal re­search in­sti­tute, San­ford-Burn­ham, which broke the news in its Beaker blog last Jan­uary, re­vealed that in the United States, more than 40 mil­lion men and 21 mil­lion women are af­fected by hair loss. Alexey Ter­skikh, Ph.D. said that they have de­vel­oped a method us­ing hu­man pluripo­tent stem cells to cre­ate new cells ca­pa­ble of ini­ti­at­ing hair growth. The method marks an im­prove­ment over cur­rent meth­ods that rely on trans­plant­ing ex­ist­ing hair fol­li­cles from one part to the other.

The Beaker re­ported the re­search team de­vel­oped a pro­to­col that coaxed hu­man pluripo­tent stem cells to be­come der­mal papilla cells. Ter­skikh added that der­mal papilla cells can­not be am­pli­fied out­side of the body, and it quickly loses its hair in­duc­ing prop­er­ties, so the team de­vel­oped a pro­to­col to drive the hu­man pluripo­tent stem cells to dif­fer­en­ti­ate into der­mal papilla cells. When trans­planted into mice, these cells con­firmed their abil­ity to in­duce hair growth. Mov­ing for­ward, the next step is to trans­plant hu­man der­mal papilla cells de­rived from hu­man pluripo­tent stem cells back into hu­man sub­jects, and that his team is seek­ing part­ner­ships to im­ple­ment the fi­nal step.

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