Prostate can­cer study

Pretoria News Weekend - - HEALTH -

A BREAST can­cer drug could also be used to stop prostate can­cer re­turn­ing, a study has found.

The drug acts by stop­ping tu­mours car­ry­ing out re­pairs to their own DNA, caus­ing the can­cer to be­come weak and die.

One of the ways prostate can­cer cur­rently gets treated is through ther­apy that re­duces SCI­EN­TISTS have iden­ti­fied a new way of spot­ting men most at risk of ill health – by test­ing their se­men.

The team found young men with the low­est sperm counts had higher rates of heart dis­ease, di­a­betes and can­cer later in life.

Re­searchers at Fred­eriks­berg Hos­pi­tal in Den­mark tracked 4 700 men for 30 years. Those with sperm counts lower than 15 mil­lion per millil­itre of fluid were 40% more likely to get heart dis­ease than those reg­is­ter­ing hor­mones which en­cour­age the growth of can­cer cells – but this also stim­u­lates a re­pair mech­a­nism that can lead to sur­viv­ing cells be­com­ing more ag­gres­sive. How­ever, re­searchers found that breast can­cer drugs called Parp in­hibitors, used with anti-hor­mone treat­ment, can stop the re­pair ef­fect. The study, by more than 40 mil­lion per millil­itre.

They needed hos­pi­tal care, on average, seven years ear­lier than men with healthy sperm counts, the re­sults of the study, pub­lished the In­sti­tute of Can­cer Re­search, car­ried out the tests on hu­man prostate can­cer tis­sue.

Lead au­thor Dr Mohammad Asim said: “Prostate can­cer is a dev­as­tat­ing dis­ease. Our ex­cit­ing dis­cov­ery will in­crease chances of sur­vival for the thou­sands of men who con­tract the dis­ease ev­ery year.” – Daily Mail in the Amer­i­can Jour­nal of Epi­demi­ol­ogy, showed. Low sperm count can re­flect poor diet and life­style, which in­creases the risk of se­ri­ous ill­ness. – Daily Mail

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