Cancer drug could help stroke patients
SYDNEY: A drug used to treat cancer patients could also be a treatment option for a leading cause of stroke in young people, according to Australian-led research.
Researchers, using mice, had discovered that cancer drug Ponatinib inhibited the signalling pathway of a specific enzyme, one of the causes of a brain blood-vessel condition linked to stroke, the Centenary Institute medical research facility said yesterday.
The medical condition, cerebral cavernous malformations (CCM), occurs when abnormal and dilated thin-walled blood vessels form clusters in the brain, altering blood flow, according to the institute.
CCM affects as many as one in 200 people and can cause bleeding, epilepsy and stroke.
The institute said the only treatment for the condition now was surgery, which was not always possible, highlighting the urgent need for non-invasive, pharmacological treatment options. |