Cancer drug could help stroke pa­tients

The Mercury - - METRO - Xin­hua/ANA

SYD­NEY: A drug used to treat cancer pa­tients could also be a treat­ment op­tion for a lead­ing cause of stroke in young peo­ple, ac­cord­ing to Aus­tralian-led re­search.

Re­searchers, us­ing mice, had dis­cov­ered that cancer drug Pona­tinib in­hib­ited the sig­nalling path­way of a spe­cific enzyme, one of the causes of a brain blood-ves­sel con­di­tion linked to stroke, the Cen­te­nary In­sti­tute med­i­cal re­search fa­cil­ity said yes­ter­day.

The med­i­cal con­di­tion, cere­bral cav­ernous mal­for­ma­tions (CCM), oc­curs when ab­nor­mal and di­lated thin-walled blood ves­sels form clus­ters in the brain, al­ter­ing blood flow, ac­cord­ing to the in­sti­tute.

CCM af­fects as many as one in 200 peo­ple and can cause bleed­ing, epilepsy and stroke.

The in­sti­tute said the only treat­ment for the con­di­tion now was surgery, which was not al­ways pos­si­ble, high­light­ing the ur­gent need for non-in­va­sive, phar­ma­co­log­i­cal treat­ment op­tions. |

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