Com­plet­ing the ac­tion of or­ganic acids

The Poultry Bulletin - - NUTRITION NEWS -

To have an even higher im­pact on Gram neg­a­tive bac­te­ria in the GIT, phy­to­chem­i­cals are com­bined with or­ganic acids. While the or­ganic acids are work­ing to re­duce the ph of the en­vi­ron­ment in the dis­so­ci­ated form and hav­ing a di­rect an­timi­cro­bial ac­tion due to the non-dis­so­ci­ated form, phy­to­chem­i­cals like cin­namalde­hyde are tar­get­ing the Ftsz pro­teins which play an es­sen­tial role in the cell divi­sion of path­o­genic bac­te­ria. By block­ing the Ftsz pro­tein, cin­namalde­hyde pre­vents the Z-ring for­ma­tion dur­ing the path­o­genic cell repli­ca­tion process, re­sult­ing in a re­duced bac­te­rial count in the GIT an­i­mals. It has been shown, that cin­namalde­hyde tar­gets only the path­o­genic bac­te­ria, not harm­ing the ben­e­fi­cial bac­te­ria. This spar­ing ac­tion of the ben­e­fi­cial bac­te­ria like it is the case of or­ganic acids and phy­to­chem­i­cals makes a big dif­fer­ence in com­par­i­son to an­tibi­otics, which are not al­ways able to tar­get only path­o­genic bac­te­ria.

Newspapers in English

Newspapers from South Africa

© PressReader. All rights reserved.