Boost­ing the ef­fect of or­ganic acids and phy­to­chem­i­cals

The Poultry Bulletin - - NUTRITION NEWS -

Be­cause Gram neg­a­tive bac­te­ria pos­sess an ex­tra outer pro­tec­tive layer, con­sist­ing mainly of lipopolysac­cha­rides makes it is very hard for the an­timi­cro­bial sub­stances to have a di­rect an­timi­cro­bial ac­tion. Be­ing able to dam­age this hy­drophilic ex­tra mem­brane of the Gram neg­a­tive bac­te­ria makes the an­timi­cro­bial sub­stances more ef­fi­cient in com­bat­ing these bac­te­ria. Per­me­abi­liz­ers have this abil­ity to fa­cil­i­tate the en­try of the an­timi­cro­bial sub­stances in the cy­to­plasm of the Gram neg­a­tive bac­te­ria, were this sub­stances can de­liver they’re di­rect an­timi­cro­bial ac­tion on the bac­te­ria.

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