Modern society’s demand for aesthetic odontology is growing and appearance and image are increasingly important. Within the wide variety of restorative options currently available to practitioners, direct composite resin techniques offer one of the best treatment alternatives and have already gained wide acceptance. Composite cements are one of the materials used most frequently in all odontology specialisms, particularly when practitioners need to join two or more heterogeneous structures. Although a multitude of composite cements have been described over the last 25 years, there has not been a protocol with indications on how to proceed in differing clinical situations. To remedy that, in this review we examine which cements — based on their chemical and mechanical properties — are most appropriate for frequently encountered clinical situations.