ASTHMA WITHOUT ASTHMA?
Researchers in the United States have identified a protein that may be causing asthma-like coughing and wheezing in children, without those kids having any kind of allergy to trigger the disease. The World Health Organization estimates around 235 million people suffer from asthma worldwide; the disease is often linked to allergies, such as a reaction to dust, pollen, smoke or pollution. The new study found that the protein TRPV1 – transient receptor potential vanilloid 1, a protein that plays a role in airway disease through mucus production, cough reflex stimulation and airway narrowing – may also be responsible for asthma-like symptoms in children even in the absence of allergies. By understanding better the mechanism by which these channels are regulated, the channels can then be targeted with a new generation of molecules and new drugs to control cough and wheezing in childhood.
235m people suffer from asthma worldwide