Crohn’s dis­ease

How does this con­di­tion dam­age the di­ges­tive sys­tem?

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Crohn’s is an in­flam­ma­tory bowel dis­ease that causes tis­sue de­struc­tion along the gas­troin­testi­nal tract, any­where from the mouth to the anus. This leads to a va­ri­ety of nasty symp­toms, such as ab­dom­i­nal pain, fa­tigue and un­ex­plained weight loss.

It’s re­ferred to as an im­mune-re­lated dis­or­der, though it’s not strictly au­toim­mune be­cause it isn’t the bod­ies’ own cells trig­ger­ing a war against it­self. In­stead, it is thought that a com­bi­na­tion of ge­net­ics, en­vi­ron­men­tal fac­tors and bac­te­ria in the gut cause the ab­nor­mal im­mune re­sponse that at­tacks healthy cells of the gas­troin­testi­nal tract. Cur­rently there is no cure for this dis­ease, though diet and med­i­ca­tion can help re­duce flare-ups.

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