Treat­ment found to shrink tu­mours in pa­tients with ter­mi­nal leukaemia

The Daily Telegraph - - News -

♦ Ter­mi­nal leukaemia pa­tients have been of­fered hope af­ter a new ther­apy was shown to shrink or make tu­mours dis­ap­pear in 70 per cent of pa­tients.

The treat­ment, called CAR T-cell im­munother­apy, ex­tracts im­mune cells from a can­cer pa­tient and mod­i­fies them in a lab so they can recog­nise leukaemia cells. The en­gi­neered cells are then in­fused back into the pa­tient where they mul­ti­ply, hunt down and kill the can­cer cells.

In a trial by re­searchers at the Fred Hutchin­son Can­cer Re­search Cen­ter, in Seat­tle, 24 pa­tients with chronic lym­pho­cytic leukaemia (CLL) who had failed to re­spond to tra­di­tional chemo­ther­apy were given mod­i­fied im­mune cells. Af­ter six and a half months, 17 out of 24 of the pa­tients had seen tu­mours shrink or dis­ap­pear.

“It was not known whether CAR T-cells could be used to treat these high risk chronic lym­pho­cytic leukaemia pa­tients,” said Dr Cameron Tur­tle, lead au­thor of the re­search pub­lished in The Jour­nal of Clin­i­cal On­col­ogy and an im­munother­apy re­searcher at Fred Hutchin­son.

“Our study shows that CAR T-cells are a highly promis­ing treat­ment.”

Around 9,500 peo­ple are di­ag­nosed with blood can­cer leukaemia each year.

Newspapers in English

Newspapers from UK

© PressReader. All rights reserved.