Schizophre­nia drug may fight can­cer

The Peterborough Evening Telegraph - - UK&WORLD UPDATE -

A DRUG used to treat schizophre­nia may pro­vide an ef­fec­tive weapon against treat­ment-re­sis­tant can­cers, re­search sug­gests. The anti-psy­chotic drug thior­i­dazine ap­pears to “tame” deadly can­cer stem cells, turn­ing them into or­di­nary non-can­cer­ous cells. Stem cells are thought to be the source of many can­cers and are of­ten im­per­vi­ous to tra­di­tional chemo­ther­apy. First iden­ti­fied in cer­tain types of leukaemia in 1997, they are now known to play a role in breast, brain, lung, gas­troin­testi­nal, prostate and ovar­ian can­cers. Sci­en­tists dis­cov­ered thior­i­dazine’s sur­pris­ing prop­er­ties af­ter screen­ing hun­dreds of com­pounds look­ing for ways of at­tack­ing can­cer stem cells.

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