Newway to pre­dict fate of pa­tients

The Press and Journal (Inverness) - - NEWS -

Changes to pro­teins in blood and spinal fluid could help doc­tors pre­dict the fate of Alzheimer’s pa­tients, re­search has shown.

As the sever­ity of the dis­ease in­creases, the mol­e­cules be­come longer, more rigid and more clus­tered, sci­en­tists have dis­cov­ered.

In­for­ma­tion about the pro­teins was com­bined with cog­ni­tive as­sess­ments to pro­vide a new way of stag­ing the ill­ness and rat­ing its pro­gres­sion.

Lead re­searcher Pro­fes­sor Mingjun Zhang, from Ohio State Univer­sity, said: “With a tool like this you may pre­dict how fast this dis­ease will go, and cur­rently we can’t do that. We just know ev­ery­one is dif­fer­ent. Look­ing at mul­ti­ple in­di­ca­tors of the dis­ease all at once in­creases the re­li­a­bil­ity of the di­ag­no­sis and prog­no­sis.”

This could speed up the de­vel­op­ment of new treat­ments, sci­en­tists be­lieve. Con­trac­tors work­ing on Lon­don’s Cross­rail project have been fined more than £1mil­lion over the death of a worker and two other in­ci­dents.

A joint ven­ture of three com­pa­nies, Bam, Fer­rovial and Kier (BFK), pleaded guilty to three of­fences fol­low­ing an in­ves­ti­ga­tion by the Health and Safety Ex­ec­u­tive (HSE).

South­wark Crown Court heard Rene Tkacik, 43, died af­ter be­ing crushed by fall­ing wet con­crete in March 2014. Two other men were in­jured in sep­a­rate in­ci­dents within days of one an­other in Jan­uary 2015.

All three in­ci­dents took place in the tun­nels around

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