Newway to predict fate of patients
Changes to proteins in blood and spinal fluid could help doctors predict the fate of Alzheimer’s patients, research has shown.
As the severity of the disease increases, the molecules become longer, more rigid and more clustered, scientists have discovered.
Information about the proteins was combined with cognitive assessments to provide a new way of staging the illness and rating its progression.
Lead researcher Professor Mingjun Zhang, from Ohio State University, said: “With a tool like this you may predict how fast this disease will go, and currently we can’t do that. We just know everyone is different. Looking at multiple indicators of the disease all at once increases the reliability of the diagnosis and prognosis.”
This could speed up the development of new treatments, scientists believe. Contractors working on London’s Crossrail project have been fined more than £1million over the death of a worker and two other incidents.
A joint venture of three companies, Bam, Ferrovial and Kier (BFK), pleaded guilty to three offences following an investigation by the Health and Safety Executive (HSE).
Southwark Crown Court heard Rene Tkacik, 43, died after being crushed by falling wet concrete in March 2014. Two other men were injured in separate incidents within days of one another in January 2015.
All three incidents took place in the tunnels around