CIT­RUS FLAVONES

Amazing Wellness - - HERBAL HEALING -

NIACINIACIN: Since the 1960s, niacin (vi­ta­min B3) hasha been known to be ef­fec­tive in low­er­ing bblood choles­terol and triglyc­eride lev­els. In fact, in nu­mer­ous clin­i­cal stud­ies niacin has demon­strated bet­ter over­all re­sults in re­duc­ing risk fac­tors for coron­nary heart dis­ease than other choles­terol­low­er­inglow agents—in­clud­ing statin drugs. Niacin typ­i­cally low­ers LDL choles­terol lev­els by 16–23 per­cent while rais­ing HDL choles­terol lev­els by 20–33 per­cent. Th­ese ef­fects, es­pe­cially the ef­fect on HDL, com­pare quite fa­vor­ably with con­ven­tional choles­terol-low­er­ing drugs. In ad­di­tion, some stud­ies have shown that niacin used in con­junc­tion with statins sig­nif­i­cantly im­proves pa­tient out­comes, as op­posed to us­ing statins alone.

Nonethe­less, many peo­ple are re­luc­tant to use niacin. The chief rea­son is that at the lev­els rec­om­mended to lower choles­terol (1,200–3,000 mg per day), it causes a hot, itchy skin re­ac­tion known as the “niacin flush.” This prob­lem has been over­come with the de­vel­op­ment of timed-re­lease “no flush” prepa­ra­tions, shown to be ex­tremely well tol­er­ated with no se­ri­ous side ef­fects. don’t eat low-mer­cury, cold-wa­ter fish, such as wild sal­mon, her­ring, or sar­dines, at least two or three times per week, take enough fish oil to get 1,000 mg daily of EPA and DHA. Fresh­ness is key, as fish oil can be­come ran­cid over time. Masley rec­om­mends test­ing one pill in a bot­tle by prick­ing the cap­sule with a nee­dle and tast­ing the oil. “It isn’t lemon­ade, but it should taste pleas­ant,” he says. MAG­NE­SIUM “If you take a cal­cium sup­ple­ment with­out mag­ne­sium, it can make a mag- Choles­terol-low­er­ing statin drugs such as Crestor (ro­su­vas­tatin) and Lip­i­tor (ator­vas­tatin) are ubiq­ui­tous th­ese days, and more are be­ing pre­scribed each year. But ques­tions re­main about their safety and ef­fec­tive­ness, and they come with their share of side ef­fects, in­clud­ing de­creased liver func­tion, in­ter­fer­ence with the man­u­fac­ture of coen­zyme Q10 (CoQ10), rhab­domy­ol­y­sis (the break­ing down of mus­cle tis­sue, which can be fa­tal), nerve dam­age, im­paired men­tal func­tion with pro­longed use, pos­si­ble in­creased risk of can­cer and heart fail­ure with long-term use, fa­tigue, and weight gain.

For­tu­nately, there are nat­u­ral al­ter­na­tives to statin drugs, in­clud­ing th­ese two stand-outs. CIT­RUS FLAVONES: Cit­rus poly­methoxly­ated flavones work by block­ing the en­zymes in the liver re­spon­si­ble for man­u­fac­tur­ing choles­terol and for triglyc­eride pro­duc­tion. For ex­am­ple, they have been shown to de­crease the pro­duc­tion of apolipopro­tein B, a struc­tural pro­tein needed for en­doge­nous syn­the­sis of LDL choles­terol. Sytri­nol and Berg­a­monte are spe­cial ex­tracts of or­anges stan­dard­ized for their poly­methoxy­lated flavonoid con­tent. Th­ese highly con­cen­trated ex­tracts have been shown to lower to­tal choles­terol, LDL choles­terol, and triglyc­eride lev­els. Clin­i­cal re­sults have shown that Sytri­nol and Berg­a­monte ex­ert ef­fects very sim­i­lar to statin drugs, but with­out side ef­fects. Specif­i­cally, they have been shown to lower to­tal choles­terol lev­els up to 30 per­cent, LDL choles­terol lev­els up to 27 per­cent, and triglyc­eride lev­els up to 34 per­cent within 4–12 weeks of use. The rec­om­mended dosage for Sytri­nol is 150 mg twice daily. For Berg­a­monte, the dosage is 500 mg once or twice daily.

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