Chronic kidney disease
N-ACETYLCYSTEINE (NAC). Tis potent antioxidant is stocked in hospital emergency rooms to treat acetaminophen overdose. Like Amanita mushrooms, acetaminophen damages the liver primarily by blocking the production of glutathione, an antioxidant required for detox. NAC is a precursor to glutathione and can heal the liver if taken soon enough. As a reliable defense against low levels of toxins, take 500–600 mg daily.
MILK THISTLE. Tis venerable herb has been used medicinally for at least 2,000 years. Recent research has clearly demonstrated that it is a powerful antioxidant, protects against liver damage, and reduces the toxic efects of drugs and other chemicals. Silymarin is the concentrated extract of milk thistle, and at least 50 percent of it consists of silybin, a potent constituent. Take 100–200 mg daily of silymarin, the concentrated extract of milk thistle.
ALPHA-LIPOIC ACID. Burton Berkson, MD, of Las Cruces, N.M., has long used this antioxidant to treat patients with liver cirrhosis, liver failure, Amanita mushroom poisoning, and other diseases. He often administers it with silymarin and selenium. Alpha-lipoic acid functions as a precursor to glutathione, helps maintain normal liver function, and can help regenerate damaged liver tissue. Take 100–200 mg daily. Amounts up to 600 mg are safe.
SELENIUM. Te liver uses selenium to make glutathione peroxidase, one of several glutathione-based compounds needed for liver detoxifcation. Ideally, it should be combined with NAC or alphalipoic acid. Take 200 mcg daily, an amount found in many multivitamin/multimineral supplements.
MULTIVITAMIN. Te B-complex vitamins and antioxidants (e.g., vitamins C and E and carotenoids) are needed to support the liver’s Phase 1 enzymes and the initial step in detoxifcation. Follow label directions in taking a daily multivitamin supplement.
AMINO ACIDS. Te liver uses these building blocks of protein to support its Phase 2 detoxifcation enzymes. Methionine and NAC are the most important amino acids in Phase 2 detoxifcation. You can also opt for a multi-amino acid supplement. Sulfur-containing amino acids, which are most abundant in animal proteins, are essential for the liver’s Phase 2 enzymes. Additional sources of sulfur include garlic and cruciferous vegetables, such as broccoli and caulifower. In practical terms, this means eating sufficient protein (e.g., chicken, turkey, fsh, and grass-fed beef) and ample vegetables.
DOCTOR’S BEST Best NAC Detox Regulators Y N E e
NATROL Alpha Lipoic Acid 600 mg Jack Challem, aka “The Nutrition Reporter,” is the best-selling author of more than 20 books on health and nutrition, including The Inflammation Syndrome. Visit him on the Web at nutritionreporter.com.