I-3-C and DIM

In­dole- 3- carbinol (I- 3- C) and the closely re­lated DIM may be the ul­ti­mate nutri­ents for healthy es­tro­gen lev­els, detox­i­fi­ca­tion—and more

Amazing Wellness - - AMAZING NEWS - Chris Oswald, DC, CNS,

Cru­cif­er­ous veg­eta­bles, such as broc­coli and kale, help pro­tect against some can­cers and en­vi­ron­men­tal tox­ins. Among their ben­e­fi­cial nutri­ents, in­dole-3-carbinol (I-3-C) is one of the most im­por­tant. It helps rid our bod­ies of tox­ins, may re­duce risk for sev­eral can­cers, and may even pro­tect against the harm­ful ef­fects of radiation.

In sup­ple­ments, I-3-C is also avail­able as DIM (3,3’- di­in­dolyl­methane). DIM is a me­tab­o­lite of I-3-C, mean­ing that our bod­ies con­vert I-3-C into DIM. Both forms have been tested in stud­ies.

Hor­mone-Dis­rupt­ing Tox­ins

Tox­ins such as bisphe­nol-A (BPA), found in many plas­tics, con­tain chem­i­cals that mimic es­tro­gen. They raise es­tro­gen lev­els, creat­ing an im­bal­ance and po­ten­tially in­creas­ing risk for hor­mone-re­lated can­cers, such as breast cancer in women and prostate cancer in men.

In women, toxin-trig­gered hor­monal im­bal­ance can ac­cen­tu­ate PMS and con­trib­ute to thy­roid dis­or­ders. The same mech­a­nism can also trig­ger or in­crease un­com­fort­able symp­toms of menopause.

In men, some con­ver­sion of testos­terone to es­tro­gen is nor­mal, but tox­ins in­flate the process, re­sult­ing in ex­cess es­tro­gen. This may con­trib­ute to an en­larged prostate and in­crease risk for prostate cancer.

How the Sup­ple­ments Work

An­i­mal and lab stud­ies show that both I-3-C and DIM stim­u­late detox­i­fy­ing en­zymes, help­ing to elim­i­nate tox­ins and harm­ful forms of es­tro­gen that can lead to cancer. These nutri­ents can also stop or slow de­vel­op­ment of cancer cells. So far, an­i­mal and lab stud­ies have shown ef­fects on breast, prostate, cer­vi­cal, ovar­ian, pancreatic, colon, and lung cancer cells.

In one an­i­mal study, I-3-C pre­vented or re­versed BPA-re­lated prostate dam­age. In an­other, I-3-C re­duced tobacco-in­duced lung cancer tu­mors. And an­other an­i­mal study found that DIM re­duces dam­age from radiation by stimulating DNA re­pair.

MEET THE EX­PERT: has ex­ten­sive ex­pe­ri­ence in clin­i­cal nutri­tion and func­tional medicine. He lec­tures on these top­ics to clin­i­cians through­out the coun­try and is the Ed­u­ca­tion Con­tent Man­ager for Na­ture’s Way Brands.

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