REDUCING BREAST CANCER RISK
In a study published in Breast Cancer: Basic and Clinical Research, Canadian researchers tested an I-3-C supplement against a placebo on 96 women. Each capsule contained lignans (beneficial fibers found in plant foods), herbs, and 200 mg of I-3-C. For 28 days, the women took one capsule of either a placebo or the supplement, twice daily. Blood and urine tests, which measured biomarkers of cancer risk, showed that those taking the I-3-C supplements significantly reduced their risk for breast and other estrogen-related cancers.
Reversing Cervical Lesions
Human studies have focused mainly on reducing cancer risk. Researchers at Louisiana State University Medical Center-Shreveport tested I-3-C on 30 women diagnosed with abnormal growths on the cervix. Such growths are known as cervical intraepithelial neoplasia (CIN), a condition that can lead to cervical cancer. In the study, published in Gynecologic Oncology, each woman took either a placebo, 200 mg of I-3-C, or 400 mg of I-3-C daily for 12 weeks. Biopsies revealed complete regression among four of eight women who took 200 mg of I-3-C and among four of nine women who took 400 mg. Other women who took the I-3-C supplements saw their risk of developing cancer reduced; those in the placebo group saw no change.