132. Karen Pritzker
Pritzker and her husband, Michael Vlock, have diversified her Hyatt Hotels inheritance by investing in stocks like Apple as well as other ventures. In 2008, the couple started Launchcapital, a venture fund that has bet on companies like Spotify and Snapchat. Three years later, they cofounded Alopexx Enterprises, a biotech investment fund whose companies are working on cures for Alzheimer’s and Pompe disease, a rare and often fatal genetic disorder.