315. Penny Pritzker
$2.6 billion Self-made Score: # Source: hotels, investments age: 58 residence: chicago J.d., m.b.a., Stanford ’84 A year ago, Pritzker was President Obama’s secretary of commerce. Reentering the private sector, she joined the board of Measure, a drone startup, in September. The Hyatt heiress manages her fortune through PSP Capital, her private investment firm, which invests in real estate, private companies and partnerships with fund managers. She’s one of 11 Pritzker billionaires.