2018 No­bel Prize in medicine

Houston Chronicle Sunday - - FROM THE COVER - SOURCE: NOBELPRIZE.ORG

Jim Al­li­son and Takusu Honjo for their dis­cov­ery of can­cer ther­apy by in­hi­bi­tion of neg­a­tive im­mune reg­u­la­tion


Can­cer Ther­apy 1966: Charles Hug­gins for his work show­ing that es­tro­gen ther­apy or an­dro­gen ab­la­tion could con­trol prostate can­cer. 1988: Trudy Elion and Ge­orge Hitchens for the de­vel­op­ment of an­ti­cancer drugs thiogua­nine and mer­cap­top­urine widely used in the treat­ment of var­i­ous leukemias as well as an antigout drug (al­lop­uri­nal) and an an­tibac­te­rial drug (trimetho­prim). 1990: E. Don­nall Thomas for the de­vel­op­ment of bone mar­row trans­plan­ta­tion as a treat­ment for leukemia. Can­cer Dis­cov­ery 1966: Pey­ton Rous for his dis­cov­ery of tu­mor-in­duc­ing viruses. 1975: David Bal­ti­more, Re­nato Dul­becco and Howard Martin Temin for their dis­cov­er­ies con­cern­ing the in­ter­ac­tion be­tween tu­mor viruses and the ge­netic ma­te­rial of the cell. 1989: J. Michael Bishop and Harold E. Var­mus for their dis­cov­ery of the cel­lu­lar ori­gin of retro­vi­ral onco­genes. 2008: Har­ald zur Hausen for his dis­cov­ery of hu­man pa­pil­loma viruses caus­ing cer­vi­cal can­cer.

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