Set in Manhattan, Nicole Holofcener’s Please Give is a sly, sometimes sad examination of the personal side effects of living in the Big Apple. It’s what’s not said that makes the movie so sweetly endearing as it follows six characters who can’t see that their lives do indeed have meaning. Rated PG-13. 91 minutes. Regal DeVargas, Santa Fe. (Robert Nott) See review, Page 60.