The Mercury News Weekend

Airlines gear up to ship vaccines to the world

Cargo comes with strict rules that must be followed

- My Niraj Chokshi

Months before anyone knew which of the coronaviru­s vaccine candidates would pull ahead or when they’d be available, airlines were trying to figure out how to transport doses around the world.

Over the summer, American Airlines, Delta Air Lines and United Airlines spoke with government officials, pharmaceut­ical companies and experts to understand where vaccines might be produced, how they would be shipped and how best to position people and planes to get them moving. More recently, they have flown batches of vaccines for use in trials and research or to prepare for wider distributi­on.

The industry will play a vital role in moving billions of doses aboard hundreds of flights in the months ahead, putting underused planes and crews to work while circulatin­g the very medicine that airlines hope will get people to book tickets again. But the flights represent just one segment of a massive, global relay race in which airlines will have to be ready to move at a moment’s notice.

“When a request comes in, it’s going to be urgent and we have to act immediatel­y,” said Manu Jacobs, who oversees shipments of pharmaceut­icals and other specialty products for United.

A Food and Drug Administra­tion vaccine advisory panel is meeting Thursday to decide whether the agency should grant emergency authorizat­ion of the Pfizer vaccine. Another vaccine, produced by Moderna, is expected to be reviewed next week. Once either is authorized, shipments are expected to begin in earnest.

One of the biggest challenges for airlines has been ensuring that vaccines are transporte­d at frigid temperatur­es. Pfizer’s must be stored at an incredibly low minus 94 degrees Fahrenheit. Moderna’s can be kept at a more easily managed minus 4 degrees.

For its vaccine, Pfizer designed special cooler containers that can be stuffed with dry ice, which is solid carbon dioxide. But aviation authoritie­s limit how much dry ice can be carried on planes because it turns to gas, making the air potentiall­y toxic for pilots and crews.

After running tests that showed it was safe, United last month asked the Federal Aviation Administra­tion to raise the limit so it could fly the Pfizer vaccine from Brussels Internatio­nal Airport to Chicago O’Hare Internatio­nal Airport, according to an FAA letter. The agency agreed, allowing the airline to carry up to 15,000 pounds of dry ice aboard a Boeing 777224 plane, compared with the previous limit of 3,000 pounds, according to the letter. A single 777 can carry up to 1 million doses, the airline said.

American and Delta are also working with the agency to increase dry ice limits for vaccine shipment. And Boeing said it has been working closely with passenger and cargo carriers and global regulators to help safely transport as much of the vaccines as possible. In service

letters, online symposiums and calls, the airplane manufactur­er has shared its own findings on dry ice emission rates and important safety procedures. Boeing also said it is working with other aerospace companies on guidance they can provide to airlines.

United declined to comment on its work with Pfizer, but said that it had been laying the groundwork to ship vaccines since the summer, an effort that involved marshaling teams from across the company and the world.

“We decided very quickly that we needed to bring some bright people together to think about how to prepare,” Jacobs said.

The scale and urgency of circulatin­g the coronaviru­s vaccine is unlike anything airlines and other logistics companies have seen before. Shipping giant UPS has been installing ultralow-temperatur­e freezer farms capable of keeping goods as cold as minus 112 degrees Fahrenheit near its air cargo hubs in the United States and Europe. The company’s health care arm has also increased production of dry ice, with U.S. facilities able to make as much as 1,200 pounds an hour. FedEx has added ultracold freezers throughout its U. S. network, too. And both companies have enormous fleets of cargo planes that will help to ferry the vaccines.

In normal times, about half of all air cargo is transporte­d by airlines, often beneath the feet of passengers. The steep decline in flights this spring removed much of that capacity, but the urgent need for masks, gloves and ventilator­s created a big opportunit­y for cash- starved carriers, allowing them to recapture at least some of that lost business. Many airlines, including United, American, Lufthansa and Virgin Atlantic, began running flights only to haul cargo, and some have gone so far as to belt boxes and goods into the seats where passengers normally sit.

Now, airlines are preparing to run vaccineonl­y flights: planes that are chock-full of freezer boxes or coolers and a skeleton crew of pilots and crew members to secure and monitor the precious cargo.

 ?? SEBASTIAN HIDALGO — THE NEW YORK TIMES ?? Workers unload cargo from a flight at Chicago O’Hare Internatio­nal Airport. The airline industry will play a vital role in moving millions of vaccine doses, putting underused planes and crews idled by the pandemic to work.
SEBASTIAN HIDALGO — THE NEW YORK TIMES Workers unload cargo from a flight at Chicago O’Hare Internatio­nal Airport. The airline industry will play a vital role in moving millions of vaccine doses, putting underused planes and crews idled by the pandemic to work.

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