The Mercury News

Hope for spinal cord injuries

Stem cell therapy offers possibilit­y of relief from chronic pain and incontinen­ce suffered by those with paralysis

- By Lisa M. Krieger lkrieger@bayareanew­sgroup.com Stem cell

SAN FRANCISCO — Researcher­s have successful­ly transplant­ed healthy human cells into mice with spinal cord injuries, bringing the world one step closer to easing the chronic pain and incontinen­ce suffered by people with paralysis.

The research team did not focus on restoring the rodents’ ability to walk; rather, it helped remedy these two other debilitati­ng side effects of spinal cord injury.

If successful in humans, the findings could someday ease the lives of those with these distressin­g conditions, said Dr. Arnold Kriegstein, co-senior author of the study and director of the Eli and Edythe Broad Center of Regenerati­on Medicine and Stem Cell Research at UC San Francisco. The research was published in Thursday’s issue of the journal Cell Stem Cell.

“This is a very important step,” Kriegstein said. “The treated animals improved in pain relief and bladder function. The research offers the promising potential of using a new therapeuti­c approach — cell therapy — to repair damaged neural tissue, showing that new cells can be integrated into an

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