OU team gets grant to find new an­tibi­otic

The Oklahoman (Sunday) - - NEWS - FROM STAFF RE­PORTS

NOR­MAN — Univer­sity of Ok­la­homa pro­fes­sors He­len Zgurskaya and Valentin Ry­benkov and their team are ad­dress­ing the crit­i­cal need for new an­tibi­otics that can fight in­fec­tions caused by the multi-drug re­sis­tant bac­terium, Pseu­domonas aerug­i­nosa, con­sid­ered an ur­gent threat by the Cen­ters for Dis­ease Con­trol and Pre­ven­tion.

The OU team re­sponded to a re­quest for ap­pli­ca­tions from the Na­tional In­sti­tute of Al­lergy and In­fec­tious Dis­eases of the Na­tional In­sti­tutes of Health, and re­ceived a fiveyear, $5.7 mil­lion grant to de­velop new, more ef­fec­tive ap­proaches against the bac­terium.

The OU-led project, “Op­ti­miza­tion of ef­flux avoid­ance and in­hi­bi­tion for an­tibi­otic devel­op­ment,” is one of only four projects that re­ceived an NIH award for the devel­op­ment of new ap­proaches to an­tibi­oti­cre­sis­tant bac­te­ria. Har­vard, Yale and the Univer­sity of Illi­nois at Ur­bana-Cham­pagne re­ceived the re­main­ing three grants.

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