Consensus line: Eagles by 61⁄ Prediction: Arizona has the league’s worst running game, averaging 57 yards per game and 2.7 per carry, while the Eagles rank third in run defense. That means the Cardinals’ chances ride on quarterback Carson Palmer’s arm, and the key to that is keeping him upright. That won’t be easy against Philly, especially if Fletcher Cox is back on the field. The Cardinals are strong defensively, but all the pieces seem to be clicking for the Eagles offense right now. They average 392.5 yards per game — third best in the league.