Low-dose aspirin: More harm than good?
Study shows daily aspirin does not prolong life, could cause hemorrhages
If you are a healthy older person and take a low-dose aspirin every day, it may be more harmful than you think.
A large clinical trial involving participants in Australia and the U.S. found a daily low-dose aspirin had no effect on prolonging life in healthy, elderly people. It also showed a higher rate of suffering from a major hemorrhage.
Results from the trial were published in the New England Journal of Medicine.
Over a four-year span starting in
2010, the trial enrolled more than
19,000 people in Australia and the U.S. who were 70 and older, or 65 for African-American and Hispanic participants because their risks of dementia or cardiovascular disease are higher. The participants did not have cardiovascular disease, dementia or a physical disability.
Roughly half of participants were given 100 mg of low-dose aspirin, while the rest were given a placebo.
The results showed the aspirin had no effect on whether people would suffer from dementia or a disability. The trial found 90.3 percent of the people who took aspirin remained alive with no persistent physical disability or dementia, compared with 90.5 percent of people on the placebo. Rates of people who suffered from disability and dementia were nearly the same.
Researchers found people taking the aspirin showed a significantly higher risk of bleeding, such as hemorrhages.
“This study shows why it is so important to conduct this type of research so that we can gain a fuller picture of aspirin’s benefits and risks among healthy older persons,” Richard Hodes, director of the National Institute on Aging, said in a statement.
Researchers said the results don’t apply to people prescribed low-dose aspirin after suffering a stroke, heart attack or other form of cardiovascular disease.