Similar to CMV is parvovirus. Parvovirus, also called ‘Fifth’s Disease’ is a common virus that can cause a flu-like illness in children with a characteristic red rash on the cheeks (‘slapped cheeks disease’). Most infections in pregnancy do not cause an infection in the fetus, but fetal infection can occur. When fetal infection occurs, severe anemia can develop in the fetus that can require treatment with intrauterine transfusion. Prevention of parvovirus is similar to CMV with good hand hygiene techniques. If there is suspected exposure, the obstetrician will determine if there is a risk fetal infection by a blood test for the mother, and if so will test with fetus with serial ultrasound examinations for 8-10 weeks to determine if there is anemia. Most fetal infections do not cause problems to the baby during the pregnancy and do not appear to cause long-term developmental problems.