Cleve­land Clinic

A His­tory of In­no­va­tion

Wellness Update - - What Doctors Know And Your Should, Too! -

In­no­va­tion has been one of Cleve­land Clinic’s cor­ner­stone val­ues since its in­cep­tion. Founded in 1921 by four renowned physi­cians, Cleve­land Clinic broke with tra­di­tional medicine by pi­o­neer­ing the idea of multi-spe­cialty group prac­tice. While this vi­sion would rev­o­lu­tion­ize pa­tient care, the founders knew this type of col­lab­o­ra­tive struc­ture would also gen­er­ate new and game-chang­ing ideas that would con­tinue to im­prove pa­tient care into the fu­ture. In­no­va­tive from the very be­gin­ning, Cleve­land Clinic’s break­through med­i­cal in­ven­tions in­clude co-founder Ge­orge Crile’s novel carotid and for­ceps clamps, as well as coro­nary artery by­pass surgery and the first face trans­plant in the United States. Not only has in­no­va­tion come from physi­cians look­ing to im­prove pa­tient care, but ideas have also been gen­er­ated from nurses and op­er­a­tions staff to ad­vance the over­all de­liv­ery of care. With an over­flow­ing pipe­line of new ideas, Cleve­land Clinic In­no­va­tions was cre­ated to keep pace with the bulging in­no­va­tion pipe­line. In­no­va­tions, the cor­po­rate ven­tur­ing arm of Cleve­land Clinic, ac­cel­er­ates the adop­tion process and en­cour­ages even more ideas from the en­tire health­care com­mu­nity. Within the ever-chang­ing health­care en­vi­ron­ment, In­no­va­tions has be­come a model of driv­ing med­i­cal in­no­va­tion. Cleve­land Clinic In­no­va­tions seeks to im­prove the lives of pa­tients by turn­ing the ideas and break­throughs of Cleve­land Clinic’s physi­cian in­ven­tors into med­i­cal prod­ucts that cre­ate new com­pa­nies, jobs and eco­nomic op­por­tu­ni­ties. Over more than a decade, In­no­va­tions has filed 1,600 patents, has more than 400 ac­tive li­censes and has 55 spin-off com­pa­nies that have re­ceived nearly $700 mil­lion in eq­uity in­vest­ment. Nearly 1,000 jobs have been gen­er­ated as a re­sult of Cleve­land Clinic In­no­va­tions and its spin-offs, hav­ing a sig­nif­i­cant im­pact on the eco­nomic growth in North­east Ohio. Lead­ers from Cleve­land Clinic In­no­va­tions ac­tively meet with physi­cians and re­searchers to en­cour­age them to think of them­selves as in­no­va­tors and to keep the in­no­va­tion process top of mind.

In­no­va­tion Sum­mit

Cleve­land Clinic In­no­va­tions hosts the an­nual Med­i­cal In­no­va­tion Sum­mit, which con­venes more than 1,000 great thinkers and lead­ers for a can­did ex­change on new med­i­cal tech­nol­ogy, its fu­ture, re­cent break­throughs and con­tin­u­ing chal­lenges. Many re­gard the meet­ing as among the pre­mier health­care gath­er­ings in the United States. The Sum­mit is built around CEOs of ma­jor cor­po­ra­tions, govern­ment ex­ec­u­tives and top in­vestors. The Sum­mit has wel­comed at­ten­dees and speak­ers from around the world to come learn, share and col­lab­o­rate on a vast plat­form of in­no­va­tion. The 2013 Med­i­cal In­no­va­tion Sum­mit – Find­ing Bal­ance through In­no­va­tion: Obe­sity, Di­a­betes & the Meta­bolic Cri­sis – will take an in-depth look at one of the na­tion’s most trou­bling health­care is­sues. This year’s Sum­mit will take place Oct. 14-16 and mark the open­ing of the Global Cen­ter for Health In­no­va­tion, Cleve­land’s new­est med­i­cal show­place. The Med­i­cal In­no­va­tion Sum­mit pro­vides an un­ri­valed per­spec­tive on the new­est med­i­cal in­no­va­tions and the fi­nan­cial driv­ers be­hind those in­no­va­tions. It is rec­og­nized for pro­vid­ing sin­gu­lar in­sights, net­work­ing op­por­tu­ni­ties and ac­tion­able take away for all par­tic­i­pants.

An­nual Top 10 list

Each year the Sum­mit con­cludes with the pre­sen­ta­tion of Cleve­land Clinic In­no­va­tions’ an­nual Top 10 list of the up-and-com­ing tech­nolo­gies that will have the big­gest im­pact on health care in the next year. Cleve­land Clinic’s cul­ture of in­no­va­tion nat­u­rally fos­ters a good deal of dis­cus­sion about new “game chang­ing” tech­nolo­gies. The pas­sion of Cleve­land Clinic’s clin­i­cians and re­searchers for get­ting the best care for pa­tients drives a con­tin­u­ous dia­logue on what state-of-the art med­i­cal tech­nolo­gies are just over the hori­zon. A rig­or­ous process is used to gather the opin­ions of Cleve­land Clinic physi­cians and re­searchers, cre­ate a field of nom­i­nated in­no­va­tive tech­nolo­gies for con­sid­er­a­tion, and de­velop a con­sen­sus per­spec­tive of what will be the Top 10 Med­i­cal In­no­va­tions for the next year. More than 110 Cleve­land Clinic ex­perts are in­ter­viewed to elicit their nom­i­na­tions. The pri­mary ques­tion is, “What in­no­va­tions are ‘game chang­ers’ in your field?” In all, th­ese in­ter­views yield nearly 150 nom­i­na­tions of emerg­ing tech­nolo­gies. A team pre­pares re­search on each tech­nol­ogy and then presents a fi­nal list of over 55 up-and-com­ing tech­nolo­gies and their data pro­files to two in­de­pen­dent panels of lead­ing Cleve­land Clinic physi­cians. In late Au­gust, each panel meets to dis­cuss, de­bate, and vote. The two panels then vote on the com­bined lists and es­tab­lish the Top 10 Med­i­cal In­no­va­tions.

Spin-offs

A look at sev­eral Cleve­land Clinic In­no­va­tions spin-off com­pa­nies that are hav­ing an im­pact on health­care to­day.

Ex­plo­rys: Ex­plo­rys was co-founded in 2009 with the Clinic to pro­vide lead­ing-edge en­ter­prise per­for­mance man­age­ment for the health­care in­dus­try. Ex­plo­rys’ plat­form has been adopted by 14 ma­jor in­te­grated health­care sys­tems with nearly 100 bil­lion data ele­ments, 31 mil­lion pa­tients, 200 hos­pi­tals, and over 100,000 providers. In ad­di­tion, Trin­ity Health just an­nounced it will im­ple­ment the en­tire suite of Ex­plo­rys’ cloud-based big data an­a­lyt­ics so­lu­tions across its 47 acute-care hos­pi­tals, 432 out­pa­tient fa­cil­i­ties, 33 longterm care fa­cil­i­ties, and nu­mer­ous home health of­fices and hospice pro­grams span­ning 10 states in or­der to con­tinue im­prov­ing its care of pa­tients, res­i­dents and com­mu­ni­ties.

Ju­ven­tas: Ju­ven­tas Ther­a­peu­tics is tak­ing re­gen­er­a­tive medicine to the next level. Ju­ven­tas was spun-off from Cleve­land Clinic in 2007 to cul­ti­vate and com­mer­cial­ize a pipe­line of re­gen­er­a­tive ther­a­pies that can treat lifethreat­en­ing dis­eases. Since its launch, Ju­ven­tas has tran­si­tioned its ther­a­peu­tic plat­form from con­cept into Phase II clin­i­cal tri­als for heart fail­ure and crit­i­cal limb is­chemia. The com­pany's lead prod­uct, JVS-100, has been shown to pro­tect and re­pair tis­sue and or­gan dam­age in a broad range of pre-clin­i­cal dis­ease mod­els.

ImageIQ: In a time when med­i­cal re­search is of­ten clouded by high costs, long time­lines, and sub­jec­tive analy­ses, ImageIQ brings clar­ity. Spun out of Cleve­land Clinic in Fe­bru­ary of 2011, ImageIQ is help­ing com­pa­nies and in­sti­tu­tions draw de­fin­i­tive, ob­jec­tive con­clu­sions in their re­search by ex­tract­ing quan­ti­ta­tive data from a wide ar­ray of im­ages. For nearly 10 years, ImageIQ’s unique ex­per­tise was re­fined in­side Cleve­land Clinic by pro­vid­ing imag­ing anal­y­sis for the Clinic’s var­i­ous re­search ef­forts. As the Clinic’s Bio­med­i­cal Imag­ing and Anal­y­sis Cen­ter’s ca­pa­bil­i­ties grew and im­age data be­came more im­por­tant in clin­i­cal and pre­clin­i­cal tri­als, the Clinic launched ImageIQ to re­spond to an­a­lyt­i­cal chal­lenges across the med­i­cal in­dus­try.

Cleve­land HeartLab: Cleve­land HeartLab, Inc.’s mis­sion is to lead in the pur­suit of the iden­ti­fi­ca­tion and preven­tion of chronic dis­ease through in­no­va­tion. Launched by Cleve­land Clinic in 2009, Cleve­land HeartLab now of­fers an ar­ray of re­li­able and af­ford­able biomark­ers that pro­vide in­sight into an in­di­vid­ual’s risk for heart dis­ease and car­diac events. Its unique pro­file of tests fo­cuses on man­ag­ing and re­duc­ing in­flam­ma­tion, and of­fers an as­sort­ment of stan­dard and ad­vanced tests that doc­tors can choose from.

Health In­for­ma­tion

For more in­no­va­tive health in­for­ma­tion geared to what you want to know, visit health.cleve­land­clinic.org

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