What hap­pens in the liver?

Living Now - - Health & Nutrition -

Ex­cess al­co­hol is very toxic to hu­man cells be­cause it is bro­ken down (or metabolised) into a sub­stance called ac­etalde­hyde, which is even more toxic than al­co­hol it­self. Ac­etalde­hyde is not cre­ated un­til the al­co­hol reaches the liver. In the liver ethanol is bro­ken down by an en­zyme called al­co­hol de­hy­dro­ge­nase into ac­etalde­hyde. The ac­etalde­hyde is then bro­ken down by an­other en­zyme called ac­etalde­hyde de­hy­dro­ge­nase, and the an­tiox­i­dant en­zymes con­tain­ing glu­tathione. Act­ing syn­er­gis­ti­cally, the ac­etalde­hyde de­hy­dro­ge­nase and the glu­tathione, turn the toxic ac­etalde­hyde into non-toxic ac­etate. Ac­etate is a sub­stance found in vine­gar.

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